Identification of Klebsiella pneumoniae that produces β-Lactamase blaKPC gene
نویسندگان
چکیده
Background Resistance of Klebsiella pneumoniae to carbapenems is mainly associated with acquired carbapenem-hydrolyzing b-lactamases [1]. These b-lactamases can be metallo b-lactamases (IMP, VIM), expanded-spectrum oxacillinases (OXA-48), or Ambler class A enzymes (NMCA, IMI, SME, GES, and KPC) [1,2]. The most common class A carbapenemases in K. pneumoniae are the K. pneumoniae carbapenemases (KPCs) [2]. Adequate detection of carbapenems resistence genes, such as blaKPCis crucial for infection control measures and appropriate choice of antimicrobial therapy [3]. In Dourados/MS there are no reports on the monitoring of KPC-producing multiresistant strains of clinical interest. The aim of this study was to identify the gene blaKPC in strains of Klebsiella pneumoniae.
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